(HANGZHOU) Introduction The Song period (960-1276) was a time of economic growth, population growth, and urbanization. Zheng et al resequenced whole genome of 48 T. rubrum strains from China and analyzed their population differentiation and drug resistance based on the sequencing data.17. Chang PK. Alsos IG, Ehrich D, Eidesen PB, et al. hangzhou population in 1235. The Song period (960-1276) was a time of economic growth, population growth, and urbanization. You can also drape it right over the shower curtain bar or shower door.It's also critical to make sure your bathroom is as well ventilated as it can be. 2001;10(4):851–857. There, he learned the Mongolian language and traditions and grew up within the Buddhist culture of former Xi Xia, After Goden’s death in 1251, his cousin Qubilai Khan (1215 – 1294) received the territories of North, View Notes - Chapter 10 Becoming.docx from HPASS 102 at Pittsburg State University, Background: Although China accounts for 7.8% of worldwide new prostate cancer (PCa) cases and 14.5% of new deaths according to GLOBOCAN 2020, the risk of, Here, we sequenced 19 PCa predisposition genes in 1,836 Chinese patients with. Genetics. List of nearest places sort by population. Hangzhou 65.2 km 244° Shangyu 59.2 km 171° Jiaxing 23.5 km 353° Shaoxing 63 km 197° Lianghu 62.3 km 169° Jiashan 37 km 22° Xiaoshan 64.9 km 230° Linping 47.9 km 253° Xiashi 8.8 km 265° Zhouzhuang 64.3 km 5° • software development by maffey.com United Nations population projections are also included through the year 2035. Previous reports have indicated that T. rubrum is highly clonal. However, Hangzhou was the center of culture in southern China, the home of poets such as Lu . A paired-end library was prepared following the steps of end repair and phosphorylation, including A-tailing, index adapter ligation, purification and PCR amplification. For each mouse, three equidistant parts were evaluated to cover the entire hippocome. 30. Mixed T. rubrum population differentiation was observed among the strains of different geographical origins. Graser Y, Kuhnisch J, Presber W. Molecular markers reveal exclusively clonal reproduction in Trichophyton rubrum. Alibaba.com DA: 15 PA: 39 MOZ Rank: 94, › Unclaimed property pennsylvania treasury, › Verizon wireless lifeline phone program, ® 2016 Keyword-Suggest-Tool.com | Email: [email protected], Newcomer funeral home dixie hwy louisville, During the 2010 Chinese census, the metropolitan area held 21.102 million people over an area of 34,585 km 2 (13,353 sq mi), Derzeit gibt es in der Stadt noch keine Straßenbahnen, The county of Qiantang was first established at this site under the Qin dynasty (221–207 bce) but did not start developing until the 4th and 5th centuries, With its Its history can be traced back over 2,200 years to the Qin dynasty (221-206 BC), Der Großteil davon müssen Flüchtlinge und Soldaten gewesen sein, die sich dort als Folge der In dem, Historians divide Song history into two eras: The Northern Song Empire (960–1127) was based north of the Yangtze River, had its capital in Kaifeng, and was smaller than the Tang Empire, The Southern Song Empire (1127–1279) had its capital at, This reputation is acquired over the last 1000 years, as the city played host to many famous poets and. With the increase in cross-strait exchanges, a small number of T. rubrum from other regions have spread and survived on the island. Dove Medical Press is a member of the OAI. Onychomycosis: clinical overview and diagnosis. Due to its economic and political importance, Hangzhou became the largest city in the world from 1180-1378 CE with a population of 1 million. 2020;6(4):310. %PDF-1.3 Mycoses. doi:10.1111/myc.13168, 24. Genomic characterization of the emerging pathogen Streptococcus pseudopneumoniae. 2016;181(1–2):89–95. 1958 - Hangzhou Zoo opens. This is usually the case in groups of many species living on islands, in lakes, and in isolated forests and habitats.2–4, Due to the limited area of oceanic islands and their varying degrees of isolation from nearby continents, they are considered ideal systems for investigating evolutionary patterns such as founder effects.5,6 Founder effects are observable in many plant and animal species; however, few studies have focused on the ecological characteristics of pathogenic microorganisms.2–4,7 Hainan Island is the southernmost tropical island in China. The target population for the KYRBS was middle and high school students in South Korea. Font Size. Su H, Packeu A, Ahmed SA, et al. The reference T. rubrum genome CMCC(F)Tli was downloaded from the NCBI Genome dataset. Mycopathologia. �x�+�����O ��b��y]���/��,�=��|4h`�if�v�h6+-�cT-'�. . Matzke NJ. Historians divide Song history into two eras: The Northern Song Empire (960-1127) was based north of the Yangtze River, had its capital in Kaifeng, and was smaller than the Tang Empire. Figure 1 Geographical distributions of T. rubrum isolates collected in China. • Top, © Copyright 2021 • Dove Press Ltd 2019;14(9):1015–1018,1023. 2017;182(1–2):77–86. Due to personnel exchanges, people from outside of Hainan enter the island carrying T. rubrum, leading to its spreading and reproduction. 2014;4(8):a019802. The second account is from a European traveler after the Mongols had become the rulers of …, A recent study reported that the polymorphisms inside the IKZF1 gene are associated with systemic lupus erythematosus in the Chinese Han, In the thirteenth and fourteenth centuries, the Mongols created the largest contiguous empire the world has ever known. This study discussed general ecological and evolutionary principles with regard to pathogenic fungi. 28. • Privacy Policy Clean data were employed for genome assembly using SPAdes v3.12.0.29 The parameter “-cov_cutoff” was set to auto. Which of the following assertions in the description of Hangzhou above would be most difficult to verify? A well-known example, China, dramatically increased its urbanization ratio, i.e., urban population as a percentage of total population, from 18% in 1978 to over 50% in 2011. 11.94 million; People also ask. Below is the list of 100 best universities for Biomedical Engineering in the World ranked based on their research performance: a graph of 5.46M citations received by 195K academic papers made by these universities was used to calculate ratings and create the top. a. Analysis of the dermatophyte Trichophyton rubrum expressed sequence tags. If you agree to our use of cookies and the contents of our Privacy Policy please click 'accept'. Assembled genomes have been uploaded to NCBI GenBank with BioProject ID PRJNA673795. Molecular epidemiological study on human superficial fungal infections in Hainan Province. Templeton AR. Southern Song Dynasty (1127-1279) These years saw Hangzhou's golden age of prosperity as it became the capital city of the Southern Song Dynasty. According to a previous report, dermatophytes are the main superficial pathogenic fungi in Hainan Province, among which Trichophyton rubrum is the dominant species.10 Dermatophytes are the most common filamentous pathogenic fungi in the clinic, which tend to infect tissues rich in keratin, such as skin and nails,11 leading to superficial infections, such as tinea cruris, tinea corporis, tinea manuum, etc. Publié le 2020-08-10 par . hangzhou population in 1235. T. rubrum cells were first added to centrifuge tubes containing lysis solution (20 mM Tris, 5 mM EDTA, 400 mM NaCl) and zirconium dioxide beads (Φ1 mm and Φ3 mm). 1966 - Hangzhou Gymnasium (arena) opens. It is ideally situated to control trade on an important river. Hangzhou comprises 10 districts, 1 county-level city, and 2 counties. Huzhou (Zhejiang), China elevation is 6 meters and Huzhou elevation in feet is 20 ft above sea level [src 1].Huzhou is a seat of a second-order administrative division (feature code) with elevation that is 552 meters (1811 ft) smaller than average city elevation in China.. Below is the Elevation map of Huzhou, which displays elevation range with different colors. ADMIXTURE (version 1.3.0) was used to analyze the population structure. Zheng H, Blechert O, Mei H, et al. In Sierra Leone, approximately 41% of the population is aged ≤15 years and only about 3.5% is aged ≥65 years.9 This means that any straightforward random sample of the population will result in an insufficient sample of older adults. YS4*���5z�h���5�z���V�S�yW_��S��0$M��yPʎb��Z$ �6-��V�ZH�߄k��8 ��"`�1�m��FX9o�����7?�"�F,��b*� �y����K�����DE���NM��-ZX|Z@��.r���HbP[���t�9����e9�^M0�o� �پDJ9h��j�� �=�Ly(J�|Wr�c��n����|v�'E9�_Wӎ3rr�y,Hs���0Ѹod�B�cc� e� �L����h9�o0���E.&���~:�o����������n�v�/m/� O�Uy5�M��� �'��X���+Ir] �V��j��� $�8JP�̿�K:d�H��N�X�YdI��)�w04��/���x⮏��%��-�d�6�8��7P���^��I>�(=�˻k 7���H]Wul�t�IQ>,i�����?�H#�^w�w�X���p5�4�?��3^-o祲7�],&���PF�W*9%! 2012;7(4):e34436. 18. In order to provide our website visitors and registered users with a service tailored to their individual preferences we use cookies to analyse visitor traffic and personalise content. Up to 4.5 h. J Parasitic Biol. His description included specialized markets that sold various food products and manufactured goods such as books, silk, and porcelains. Text Edge Style. Rural Population* Term Birth Urban Population* Substances LTF protein, human Lactoferrin Grant support 2017YFD0400601/National Key R&D Program of China . Hangzhou is a famous tourist city in China. The low genetic polymorphism observed verified the low levels of variation previously reported among T. rubrum.17,24 In addition, no significant Fst values were obtained between different geographical populations (Figure 4). Martinez DA, Oliver BG, Gräser Y, et al. doi:10.1371/journal.pone.0017172, 6. Hangzhou became the largest city in the world from 1180-1378 CE with a population of 1 million. With a concentration of 2.8–90 μg mL −1 and a 0.9996 calibration correlation coefficient, the DAPH contents in the FDGN extract, BDGN extract, and raw DGN extract were 7.7108 ± 0.06 mg g −1, 6.3355 ± 0.02 mg g −1, and 6. Register your specific details and specific drugs of interest and we will match the information you provide to articles from our extensive database and email PDF copies to you promptly. 2012;3(5):e00259–00212. That Hangzhou had a large population B. Updates on the epidemiology of dermatophyte infections. UK VAT Group: GB 365 4626 36. Domestication and divergence of Saccharomyces cerevisiae beer yeasts. White TJ, Bruns T, Lee S, Taylor J. PCR Protocols: A Guide to Methods and Applications. 29. Based on our findings, we proposed that the T. rubrum population on Hainan Island originated from a specific historical event and reproduced after being introduced to the island. Plots were done using the R package ggplot2.34. 1980;94(4):1011–1038. Chart and table of population level and growth rate for the Hangzhou, China metro area from 1950 to 2021. AD Scientific Index 2021. Hangzhou is the birthplace of Dragon Well (Longjing) tea, which is . Wang L, Ma L, Leng W, et al. Blutfield MS, Lohre JM, Pawich DA, Vlahovic TC. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. The ten urban districts occupy 8,292.31 km 2 (3,201.68 sq mi) and have a population of 8,241,000, in which there are six central urban districts and four suburban districts. East Asia (Modern World Cultures) | Douglas A. Phillips | download | Z-Library. doi:10.1111/j.1461-0248.2008.01179.x. Bioinformatics. European and American population [10, 11], however, there is a lack of knowledge about the vaginal microbiome in Chinese pregnant women. The metro area population of Hangzhou in 2020 was 7,642,000, a 2 . Hangzhou's 2020 population is now estimated at 7,642,147.In 1950, the population of Hangzhou was 610,395.Hangzhou has grown by 984,411 since 2015, which represents a 2 . Genetics. Whole-genome resequencing of Trichophyton rubrum provides insights into population differentiation and drug resistance. Syst Biol. Notably over the last two decades, the Asia-Pacific urban proportion has risen by 29%, more than any other region in the world (UNPD, 2010 & 2009). When K value varied from 2 to 10, the populations were all mixed with no obvious resolution. Epidemiology and diagnostic perspectives of dermatophytoses. The distance from Xinli to China's capital Beijing (Beijing) is approximately 1,235 km / 768 mi (as the crow flies). Wickham H. Ggplot2: Elegant Graphics for Data Analysis. We offer real benefits to our authors, including fast-track processing of papers. From editorial acceptance to publication. Average concentrations were 310 items kg −1 (min - 0 items kg −1 ; max - 2760 items kg −1 ), and counts in areas with plastic mulching were more than twice as high as in those without. 14. Population: 784,000. 1. In general, Zhejiang c J Clin Microbiol. Mycopathologia. �X�X��T��P^�&��s~Y0i-�rf,������W��(pŗ�Ye�re1��E3�C7��nk�����~z'h���mI�t#�)� Ǒ%��3�#P��Ôk��0�4�#{��'d�(�u߾Xe��c�H����9@�8�5�G4�u�N^��� [m�V�{��aq@f�;&Y�T��z��;��]�.��&���)d� k�;�"�~�r萃��eT��=~�_Uh7�#40� ;ς�2����w;�U���8�/ӻ��8�1���؇#ups5�2�j��A�2Pu��� K*K�n���J��2ՙ�R]���!��æ���r:��菛�XM>�*���UY|� ��a5yDž* The cells were disrupted by shaking using a rapid biological sample preparation system at low temperature (Life Real, Hangzhou, China). Petrucelli MF, Abreu MH, Cantelli BAM, et al. Aβ1-42, GFAP, NeuN, caspase-3 and CD31 were detected by the second antibody (anti-mouse and anti-rabbit; Alexa Fluor 488 and 695, (Multi Sciences Biotech, Hangzhou, China)) coupled with Alexa fluor fluorescent dye. doi:10.1002/bies.20745, 2. The authors declare no conflicts of interest. According to Marco Polo. In addition, the genetic diversity (π) of the Hainan isolates was low and showed no significant difference from that of isolates from other sites.Conclusion: This study is the first to discuss general ecological and evolutionary principles related to pathogenic fungi. open access to scientific and medical research. doi:10.1007/s11046-015-9941-y, 27. To maximize the ecological and geographical breadth of their origins, this collection included 89 strains from Hainan Island that were geographically independent from inland areas and 115 strains from inland cities. After the library was qualified, the Illumina HiSeq X platform was used for high-throughput sequencing, and paired-end reads of 150 bp were obtained, resulting in approximately 3 G of sequencing data for each strain. Blue Branch lines represented bootstrap supports >90%. Peter J, De Chiara M, Friedrich A, et al. Mycoses. Dr Jeffrey Weinberg, Yuanyuan Geng,1,* Weiwei Wu,2,3,* Rouyu Li,4– 6 Juan Xu,1 Ruixue Gu,1 Jiejie Lu,2 Wenai Zheng,7 Fei Zhao,1 Jianzhong Zhang,1 Jie Gong1 1National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China; 2Department of Dermatology, The Fifth People’s Hospital of Hainan Province, Haikou, People’s Republic of China; 3National Clinical Research Center for Skin and Immune Disease, Beijing, People’s Republic of China; 4Department of Dermatology, Peking University First Hospital, Beijing, People’s Republic of China; 5Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, People’s Republic of China; 6Research Center for Medical Mycology, Peking University, Beijing, People’s Republic of China; 7Department of Laboratory Medicine, The Fifth People’s Hospital of Hainan Province, Haikou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Gong Tel +86 10 5890 0368Email [email protected]Background: Founder events have been observed among numerous plants and animal species living on oceanic islands due to the geographic separation of these islands and the small amount of original life they harbor. 10. Long-distance plant dispersal to North Atlantic islands: colonization routes and founder effect. However, it’s reasonable for T. rubrum to present less SNPs. Maybe also interesting: Distances from Xinli to the largest places in China. Selected Publications: “Circulation and Flow: Immanent Metaphors in the Financial Debates of Northern Song China (960-1127, “Notebooks (biji) and Shifting Boundaries of Knowledge in Eleventh-Century China,” The Medieval Globe 3:1 (2017), 129-168.“Nature’s Capital: The City as Garden in The Splendid Scenery of the Capital (Ducheng, Les Églises Chrétiennes de Dieu [B7_5] Le Mysticisme Chapitre 5, L’Islam [B7_5] (Édition 2.5 19900810-20050209-20170610). X-axis: scaffolds exhibit in order. 2014;63(6):951–970. in Chinese. Clinical, Cosmetic and Investigational Dermatology, http://data.cma.cn/data/cdcdetail/dataCode/SURF_CLI_CHN_MUL_MON.html, Creative Commons Attribution - Non Commercial (unported, v3.0) License. A Celtic tribe is believed to have founded this city on an island in the midst of a river in the latter part of the third century BC. Zhejiang Sheng's capital Hangzhou (Hangzhou) is approximately 114 km / 71 mi away from Xinli (as the crow flies). Hedrick PW, Gutierrez-Espeleta GA, Lee RN. The current metro area population of Hangzhou in 2021 is 7,846,000, a 2.67% increase from 2020. After 7 days’ cultivation at 28°C, the cultures were separated into monoclonal cultures and identified by the molecular sequencing of their ITS regions.26,27 The primer sequences were as follows: ITS1 (forward): 5ʹ-TCCGTAGGTGAACCTGCGG-3ʹ, ITS4 (reverse): 5ʹ-TCCTCCGCTTATTGATATGC-3ʹ28. Founder effect in an island population of bighorn sheep. For each mouse, three equidistant parts were evaluated to cover the entire hippocome. • Recommend this site • Web Design by Adhesion. Hangzhou population in 1235. Battery Type. 2008;11(6):609–623. doi:10.1128/JCM.00352-19, 20. Most other cities can only boast of one special product; what makes the capital unique is that it gathers goods from all places. Genetica. Data of 2054 participants were collected in a hospital in Hangzhou, Zhejiang province, China. 1950 610,000. We also retain data in relation to our visitors and registered users for internal purposes and for sharing information with our business partners. Cell. doi:10.1128/mBio.00259-12, 26. 按这个变化率来推测全年数据，今年全国出生人口可能会降到998万左右，总人口可能出现负增长 . What Hangzhou is most famous for, from a local. Mycoses. Mycopathologia. Persinoti GF, Martinez DA, Li W, et al. The company's net profit attributable to shareholders was 47.59 billion yuan. Hughes AR, Inouye BD, Johnson MT, Underwood N, Vellend M. Ecological consequences of genetic diversity. Zhejiang cuisine, alternatively known as Zhe cuisine, is one of the Eight Culinary Traditions of Chinese cuisine. doi:10.1111/j.1439-0507.2008.01606.x. Answer: Hangzhou (杭州市), China (Administrative unit: Zhejiang 浙江省) - last known population is ≈ 5 162 100 (year 2010).This was 0.385% of total China population.If population growth rate would be same as in period 2000-2010 (+4.76%/year), Hangzhou population in 2021 would be: 8 613 806*. AoB Plants. Its reproduction may be asexual, or its sexual reproduction occurs infrequently,24,38 which could be responsible for the low frequency of genetic differentiation observed. Phylogenetic analysis and genetic polymorphisms were studied based on a total of 41,409 high-quality whole-genome SNPs.Results: The majority of the isolates from Hainan Island clustered together. The above percentage of manuscripts have been rejected in the last 12 months. This work is published and licensed by Dove Medical Press Limited. Hangzhou Urban Area Population History. Mol Ecol. Phylogenetic relationship of the 204 T. rubrum from different geographical regions was shown by a maximum likelihood phylogenetic tree, which resulted from the 41,049 confident SNPs. As a by-product in the sericulture industry, mulberry branches are not currently utilized effectively. Due to the short evolutionary time (being the epidemic strain worldwide since the 1950s), only a differentiation trend was observed between the population of Hainan Island and those of other regions. Persinoti GF, Martinez DA, Li W, et al. This site is owned and operated by Informa PLC ( “Informa”) whose registered office is 5 Howick Place, London SW1P 1WG. According to epidemiological data, T. rubrum is the dominant superficial pathogen, accounting for more than 80% of dermatophyte infections.14 It survives in the environment for at least six months, capable to be universally infected,15 besides, its infections are mostly chronic and easy to relapse.16,17 Due to its biological characteristics and prevalence, T. rubrum has become a model organism for studying human pathogenic filamentous fungi. Dermatophyte infection is the most common human fungal infection, affecting 20–25% of the global population, and asymptomatic carriers account for 30–70% adult population,12,13 resulting in a great burden of disease and medical burden. Shock. 昆明辅警招聘笔试内容是什么？ 昆明辅警招聘笔试内容是什么？ 考试. Jialing 20 is an artificial triploids mulberry that widely cultivated in southwest China. A total number of 41,049 SNPs were identified among 204 isolates, which was much lower than other fungal genera (2,454,052 SNPs among 157 Saccharomyces cerevisiae isolates;32 589,255 SNPs among 182 Candida albicans isolates,30 or 300,116 SNPs among L- and S-type Aspergillus flavus isolates,36 etc.). Adult tinea capitis in China: a retrospective analysis from 2000 to 2019. It revealed the list of 2015 Amazing China-ten most attractive cities in the eyes of foreign talents, they were Shanghai, Beijing, Hangzhou, Shenzhen, Tianjin, Qingdao, Suzhou, Guangzhou, Xiamen and Jinan. It is the capital and most populous city of Zhejiang Province in East China. Danecek P, Auton A, Abecasis G, et al. The evolutionary relationships of the strains from different regions were not completely separated according to the phylogenetic tree, but between the lineages, we observed geographical patterns in which the majority of isolates from Hainan Island clustered together (Figure 2, pink area), suggesting an independent evolutionary trend of these strains. 2011;27(15):2156–2158. Capital Places Quiz. 750 g/1 ms. 750 g/1 ms. Mycoses. From submission to first editorial decision. 13. T. rubrum genomes were sequenced by Illumina technology (Novogene, Beijing, China) after library construction. Table 1 Ecological and Geographic Information of T. rubrum Isolates in This Study. The immunologic response to Trichophyton rubrum in lower extremity fungal infections. doi:10.1111/jam.14419, 37. In dermatophytes, sequencing and analysis of the genome data about some important species have been reported, including Microsporum canis, T. rubrum, T. violaceum, etc., which provide insights into their population differentiation and potential pathogenic genes.24,25 Compared to the genetic variation of other fungal pathogens, the genetic diversity level within T. rubrum is significantly low. In the formal exercise intervention, the treadmill . doi:10.1111/myc.12315. Badali H, Mohammadi R, Mashedi O, de Hoog GS, Meis JF. Furthermore, because of the large population and the busy commercial traffic, there is a demand for everything." - Description of Hangzhou, capital of the southern Song dynasty, circa 1235 C.E. 1Zhejiang Provincial Centre for Disease Control and Prevention. Different evolutionary processes in shaping the genetic composition of Dendrobium nobile in southwest China. . J Fungi. J Clin Microbiol. To examine the population genetic characteristics of T. rubrum in China, the genomes of 204 T. rubrum isolates collected from 7 provinces were sequenced and analyzed. China is a developing country with the largest population in the world, and CKD is prevalent in the country;3 however, there has been no well-established national surveillance system for kidney disease. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. doi:10.1128/mBio.01286-19. hangzhou population in 1235 Ever since ancient times, Hangzhou, known as the "Capital of Tea in China", has been a famous tea-production base in China.Tea culture is an important feature of the city. The phylogenetic characteristics and genetic polymorphism distribution pattern of T. rubrum were studied by analyzing genomic sequences. Canals lose business to railroads. The authors confirm that the ethical policies of the journal, as noted on the journal’s author guidelines page, have been adhered to and the appropriate ethical review committee approval has been received. In 2010, the population of Hangzhou had amounted to . It derives from the traditional ways of cooking in Zhejiang Province, which is located south of Shanghai and centred around Hangzhou, a historical Chinese capital. where is regina sk, payday regina sk canada, regina sk time zone, payday regina sk sask, city of regina sk map, payday regina sk saskatchewan, payday regina sk cz, regina sk population Hangzhou and prices provided with minor accidents is Steven Kings, or shares take in force on Delhi i. Figure 4 Genetic differentiation in the 204 surveyed T. rubrum strains. Song cities, centers of government and commerce, were among the largest cities of the world. 50% 75% 100% 125% 150% 175% 200% 300% 400%. Aβ1-42, GFAP, NeuN, caspase-3 and CD31 were detected by the second antibody (anti-mouse and anti-rabbit; Alexa Fluor 488 and 695, (Multi Sciences Biotech, Hangzhou, China)) coupled with Alexa fluor fluorescent dye. The statistic shows the population of Hangzhou in China from 1980 to 2010, with forecasts up until 2035. In brief, genomic DNA was randomly fragmented using a Covaris ultrasonic disruptor. New York: Springer; 2009. A Chinese writer vividly described Hangzhou in 1235. The unique geographical features of Hainan Island make it an ideal model for the study of evolutionary processes.8,9. This study collected and sequenced 204 T. rubrum strains from different regions in China, aiming to describe the genetic characteristics of T. rubrum population in greater coverage, making the results more representative, and providing theoretical foundation for the formulation of treatment strategies in clinic.
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